Monocyte Activation Testing for Successful Clinical Trials
Contamination Risks in Product Development: A primary challenge in therapeutic innovation
Unexplained failures in clinical trials
Costly losses in drug and device development
High cost of medical care
Lives lost
Our Solution: The Monocyte Activation Test (MAT)
Comprehensive: detects all fever-causing substances
Biologically relevant: based on human blood cells, not animal
Quantitative and consistently accurate
Rapid service: test results in less than 5 days
One Test for All Required Quality Controls
A finished product needs:
Sterility Test
Mycoplasma Test
Endotoxin/Pyrogen Test by BET/RPT
Pattern recognition receptors
All contaminants act on human blood cells through one or more proteins of the protein families known to be present in human blood cells.
PyroDex vs. Current Microbial Detection Tests
The MAT: a relevant alternative to the Rabbit Pyrogen Test (RPT)
• Comprehensive
• Quantitative
• Versatile and scalable
• Relatively fast
MAT—Safer medical drugs and devices: better treatment to save more lives
Partnership Opportunities
PyroDex offers
MAT preclinical testing for therapeutic products of all sizes
Parenteral medical drugs
Implantable medical devices
Subcontract MAT testing for CDMOs and CROs
Pre-clinical studies in animal models
Different phases of clinical trials
Contact Us Today
Djikolngar Maouyo, Ph.D.