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LAL testing is also known to yield false negatives, so when no contamination is detected, products must be sent for further costly and time-consuming tests using rabbits. https://images.squarespace-cdn.com/content/v1/58c6db086a4963946cb5acd1/1490818090208-TXMKKA6EL9EVE7ACD6WT/rabbit.png Microbial Contamination Testing - MAT - Technology for Pyrogen Testing - Inaccuracy of Animal testing The rabbit pyrogen test’s accuracy as a safety test for therapeutic products is currently questioned, especially for testing intramuscular or subcutaneous vaccine injections. Results can be inconsistent, since sensitivity varies from one rabbit to another depending on age, strain, sex, and environmental factors. https://images.squarespace-cdn.com/content/v1/58c6db086a4963946cb5acd1/1490818107533-3AGREIZB28ED4WD4EHGA/image-asset.png Microbial Contamination Testing - MAT - Technology for Pyrogen Testing - Prompt, reliable findings Using an automated MAT (monocyte activation test) technology, PyroDex can provide you with a full report on test results in five days, or for expedited service, within 48 hours — enabling you to get your products to market faster. https://images.squarespace-cdn.com/content/v1/58c6db086a4963946cb5acd1/1490818117556-LTWA51Y7LXEKX5AKLMEF/results.png Microbial Contamination Testing - MAT - Technology for Pyrogen Testing - Comprehensive detection PyroDex uses an FDA-approved technology that detects pyrogens (fever-causing substances) of all types — including endotoxins, and non-endotoxin pyrogens from Gram-positive bacteria, viruses, molds, and yeasts — so you can promote your products’ safety with complete assurance. https://images.squarespace-cdn.com/content/v1/58c6db086a4963946cb5acd1/1490818124357-Z8Y7S34MGOTSDTVXQSF5/image-asset.png Microbial Contamination Testing - MAT - Technology for Pyrogen Testing - Consistent, quantifiable results PyroDex’s MAT technology uses human-sourced monocytes to mimic the fever response to contaminants in vivo and is similar to the reaction when therapeutic products are administered to humans. 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